Research overview

NAD+ Nicotinamide Adenine Dinucleotide

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme central to cellular energy and redox metabolism, studied for mitochondrial-function and cellular-aging research.

Compound profile

Name: NAD+
Scientific name: Nicotinamide Adenine Dinucleotide
Molecular formula: C21H27N7O14P2
Molecular weight: 663.43 g/mol
Category: Research peptide (research use only)
Documentation: Third-party tested; per-batch COA when available

Certificates of Analysis

Scientific literature

11 curated peer-reviewed studies and public references for NAD+. Each opens at its original source; provided for research reference only.

Aging Cell · 2025

Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double-Blind Randomized Crossover Placebo-Controlled Trial

Nature Metabolism · 2025

NAD+ precursor supplementation in human ageing: clinical evidence and challenges

Nature Communications · 2024

Nicotinamide riboside for peripheral artery disease: the NICE randomized clinical trial

Current Diabetes Reports · 2024

Effects of Nicotinamide Mononucleotide on Glucose and Lipid Metabolism in Adults: A Systematic Review and Meta-analysis of Randomised Controlled Trials

Frontiers in Endocrinology · 2022

Association of Human Whole Blood NAD+ Contents With Aging

GeroScience · 2022

The efficacy and safety of beta-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial

Circulation · 2021

NAD+ Metabolism in Cardiac Health, Aging, and Disease

Nature Metabolism · 2020

NAD+ Homeostasis in Health and Disease

Frontiers in Aging Neuroscience · 2019

A Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD+

Circulation Research · 2018

Sirtuins and NAD+ in the Development and Treatment of Metabolic and Cardiovascular Diseases

Trends in Cell Biology · 2014

NAD+ and Sirtuins in Aging and Disease

Literature last updated July 27, 2026

For Research Use Only

All products currently listed on this site are for research purposes only. Not for human or animal consumption. Intended strictly for qualified laboratories performing controlled in-vitro or analytical research. No medical, diagnostic, or therapeutic claims are made for any product. The references above are provided for research reference only and do not constitute claims about any product sold here.

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